Very old English nouns may exhibit an irregular relationship between the singular and plural forms, as in foot and feet, mouse and mice. But most nouns construct the plural form in a simple, predictable way from the singular form. Rarely, though, one finds a word that is, or seems to be, a plural form, which would be judged to have been created in the regular way, except that there is scanty evidence of the presumptive singular form.
to be in cahoots to be in the doldrums to drain the dregs to be down in the dumps to have the heebie jeebies the hustings to merit kudos the measles the mumps the munchies to suffer from the runs the screaming mimi's the willies the yaws